Prognostic value of lymph node dissection in malignant melanoma
C. P. Karakousis, M. K. Seddiq and R. Moore
Retrospective review of 199 patients with malignant melanoma who had
regional node dissection showed that the median survival rates of patients
with histologically negative nodes was more than threefold higher than that
of patients with histologically positive regional nodes. In the patients
with positive nodes, survival was related to the number of nodes involved.
Patients with one, two, and three or more positive lymph nodes had a
tumor-free five-year survival rate of 41%, 30%, and 18%. Patients who
required regional node dissection for positive palpable nodes in one month,
one year, or longer than one year from the excision of the primary tumor
had a median survival of 21.5, 22, and 44 months.
