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Leukocytosis at Termination of Antibiotic TherapyIts Importance for Intra-abdominal Sepsis
E. Stan Lennard, MD, ScD;
Barbara H. Minshew, PhD;
E. Patchen Dellinger, MD;
Margaret Wertz, RN
Arch Surg. 1980;115(8):918-921.
Abstract
Postoperative outcomes of 31 afebrile patients who had responded to treatment for intra-abdominal sepsis were compared based on the presence or absence of leukocytosis (WBC count > 10,000/cu mm) at the conclusion of antibiotic therapy. In 68% of the patients who had leukocytosis, postoperative septic complications developed within two months of their operation. In patients without leukocytosis, complications developed in only 8.3%. Afebrile patients who exhibit leukocytosis but have responded clinically to treatment are at risk for postoperative infection and multisystem failure.
(Arch Surg 115:918-921, 1980)
Author Affiliations
From the Department of Surgery, University of Washington School of Medicine, Seattle.
Footnotes
Accepted for publication April 30, 1980.
Reprint requests to Department of Surgery, University Hospital RF-25, Seattle, WA 98195 (Dr Lennard).
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