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A Preliminary Report

Vettivetpillai Ketharnathan, MB, FRACS, FRCS; Bruce A. Christie, MVSc

Arch Surg. 1980;115(8):967-969.

Abstract
• Collagen tubes grown in sheep around Silastic mandrils were tanned in neutral, buffered glutaraldehyde and deployed as arterial xenografts in the aorta of dogs. The grafts maintained patency for up to three years and did not show any signs of aneurysmal dilation or luminal narrowing. The lumen became lined with a neointima, and host collagen was deposited around the periphery so that the thickness of the wall of the graft approximated that of the aorta.

(Arch Surg 115:967-969, 1980)

Author Affiliations
From the Cardiothoracic Unit, Royal Melbourne Hospital (Dr Ketharnathan), and Veterinary Clinical Centre, University of Melbourne (Dr Christie).

Footnotes
Accepted for publication March 25, 1980.

Reprint requests to Suite 21, The Private Consulting Rooms, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia (Dr Ketharnathan).

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