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A Five-Year Clinical Experience

John C. Norman, MD; J. Michael Duncan, MD; O. Howard Frazier, MD; Grady L. Hallman, MD; David A. Ott, MD; George J. Reul, MD; Denton A. Cooley, MD

Arch Surg. 1981;116(11):1441-1445.

Abstract
• An intracorporeal (abdominal) left ventricular assist device (ALVAD) or partial artificial heart was designed, developed, extensively tested in vitro and in vivo, and subsequently approved for controlled clinical trials in institutions. The ALVAD is pneumatically actuated, synchronously or asynchronously, with an external console and is interposed between the apex of the left ventricle and infrarenal abdominal aorta. The implantation techniques are straightforward and replicable. The ALVAD was used in weaning from cardiopulmonary bypass to support the circulation in cardiogenic shock after infarction and as a bridge to cardiac transplantation. It was found that the profoundly depressed human left (and right) ventricles initially incapable of ejection can recover if totally supported with this device. This experience strongly suggests that ALVADs should be used early in instances of intra-aortic balloon pump inadequacy.

(Arch Surg 1981;116:1441-1445)

Author Affiliations
From the Section of Surgery (Drs Norman, Duncan, Frazier, Hallman, Ott, Reul, and Cooley) and Cardiovascular Surgical Research Laboratories (Dr Norman), Texas Heart Institute, St Luke's Episcopal and Texas Children's Hospitals, Houston.

Footnotes
Accepted for publication July 17, 1981.

Read at the 29th scientific meeting of the International Cardiovascular Society, Dallas, June 11, 1981.

Reprint requests to Texas Heart Institute, PO Box 20269, Houston, TX 77025 (Dr Norman).

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