A device to stimulate the mechanical component of malignant bowel obstruction
I. D. Fraser, R. E. Condon, W. J. Schulte, J. J. DeCosse and V. E. Cowles
A predictable and progressive experimental intestinal obstruction,
simulating a malignancy but without neoplastic change has been produced by
application of a silicone rubber ring around the bowel of 20 rats, seven
dogs, and five monkeys. Serosal reaction produced fibrous tissue that
resulted in an "apple core" obstruction. An easily assembled extraluminal
balloon device of silicone rubber can be used to produce acute and
progressive experimental obstruction, especially of the large bowel.