This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (20)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Diagnostic Value of Biochemical Investigations

Michel Huguier, MD; François Lacaine, MD

Arch Surg. 1981;116(4):399-401.

Abstract
• The results of biochemical estimations in 116 patients with known gastrointestinal cancer but no clinically detectable metastatic hepatic disease have been analyzed statistically. The most sensitive and the most specific tests for the presence or absence of hepatic metastasis were measurements of alkaline phosphatase and -glutamyl transpeptidase. The predictive value for the absence of hepatic metastasis when the test results were normal was about 90% for alkaline phosphatase, -glutamyl transpeptidase, lactate dehydrogenase, and serum aspartate aminotransferase. The best predictive value for the presence of hepatic metastasis (80%) was given by abnormal results of combined estimations of -glutamyl transpeptidase and lactate dehydrogenase, and of -glutamyl transpeptidase and serum aspartate aminotransferase.

(Arch Surg 1981;116:399-401)

Author Affiliations
From the Service de Chirurgie Généralé et Digestive, Hôpital Rothschild, Paris.

Footnotes
Accepted for publication Nov 25, 1980.

Reprints not available.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Detection of Hepatic Metastases from Cancers of the Gastrointestinal Tract by Using Noninvasive Imaging Methods (US, CT, MR Imaging, PET): A Meta-Analysis
Kinkel et al.
Radiology 2002;224:748-756.
ABSTRACT | FULL TEXT  

Hepatic Flow Scintigraphy in Evaluation of Hepatic Metastases in Patients With Gastrointestinal Malignancy
Huguier et al.
Arch Surg 1993;128:1057-1059.
ABSTRACT