This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal

A Novel Co-mutation

Michael O'Holleran, MD; Ronald C. Merrell, MD

Arch Surg. 1981;116(4):476-477.

Abstract
• Pseudoxanthoma elasticum and polyposis coli are inherited conditions not, to our knowledge, previously reported to coexist. The spontaneous appearance of both conditions in a 62-year-old woman may represent a novel mutation. The defective cell in both pseudoxanthoma and some of the extracolonic manifestations of Gardner's syndrome is the fibroblast; therefore, this case may represent a unique variation of Gardner's syndrome.

(Arch Surg 1981;116:476-477)

Author Affiliations
From the Department of Surgery, Stanford University Medical Center, Stanford, Calif.

Footnotes
Accepted for publication Nov 5, 1980.

Reprint requests to Department of Surgery, Stanford University Medical Center, Stanford, CA 94305 (Dr Merrell).