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HeparinEfficacy and Safety After Arterial Operations
COL George J. Collins, Jr, MC, USA;
COL Norman M. Rich, MC, USA;
LTC G. Patrick Clagett, MC, USA;
MAJ Michael J. Spebar, MC, USA;
LTC James M. Salander, MC, USA
Arch Surg. 1981;116(8):1077-1081.
Abstract
• Hemorrhage is the most serious side effect of heparin sodium use. Under several circumstances, one may need to administer heparin to patients who have had recent peripheral vascular operations. Avoiding an inordinate number of hemorrhagic complications is mandatory after such operations. Side effects appear to be minimized by administering heparin by continuous intravenous (IV) infusion. Nineteen patients with recent peripheral vascular operations were given heparin by continuous IV infusion. A known hemorrhagic complication developed in only one. The degree of hemorrhage was mild and did not necessitate cessation of treatment with heparin. None of the patients whose mean activated partial thromboplastin times were in the therapeutic range experienced thrombotic complications while receiving heparin.
(Arch Surg 1981;116:1077-1081)
Author Affiliations
From the Peripheral Vascular Surgery Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC, and the Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Md.
Footnotes
Accepted for publication Feb 18, 1981.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.
Reprint requests to Cardiothoracic Surgery Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234 (Dr Collins).
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