You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


Advertisement

ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | RSS | Access Rights | Sign In


  Vol. 117 No. 1, January 1982 TABLE OF CONTENTS
  Online Only
 •  Online First Table of
Contents
  ARTICLES
 •Online Features
 This Article
 •References
 •Full text PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Citing articles on Web of Science (80)
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Delicious Add to Digg Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this?

Prothrombin and Partial Thromboplastin Times as Preoperative Screening Tests

John M. Eisenberg, MD; John R. Clarke, MD; Steve A. Sussman, MD

Arch Surg. 1982;117(1):48-51.


Abstract



• Preoperative tests of coagulation function have been suggested to detect patients who are likely to have abnormal bleeding during and after surgery. A study was designed to determine the yield of prothrombin time (PT) and partial thromboplastin time (PTT), both in discovering patients who are at risk for abnormal bleeding and in inducing changes in patient care or outcome. Of 750 patients on three surgical services, 611 (81%) patients had no indication of a bleeding disorder on history or physical examination. Of the 139 patients who had clinical indications, 25 (18.0%) patients had an abnormal PT or PTT. Of the 611 patients without clinical indications, 480 patients had the PT or PTT determined, and 13 (2.7%) patients had abnormal results. One (0.2%) of the 480 patients might have benefited from the test result (this patient required a second operation to control arterial bleeding). The prolonged PT or PTT was of no apparent clinical importance in the remaining 12 patients without indications of bleeding disorders preoperatively. The low yield of the PT and PTT in detecting unsuspected bleeding disorders preoperatively was further obscured by the larger number of apparently false-positive results (2.3%).

(Arch Surg 1982;117:48-51)



Author Affiliations



From the Section of General Medicine, Department of Medicine, University of Pennsylvania, Philadelphia (Dr Eisenberg) and the Departments of Surgery (Dr Clarke) and Obstetrics and Gynecology (Dr Sussman), Medical College of Pennsylvania, Philadelphia. Dr Eisenberg is the Sol Katz Associate Professor of General Medicine.


Footnotes



Accepted for publication May 20, 1981.

Reprint requests to Section of General Medicine, Third Floor, Silverstein Pavilion, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104 (Dr Eisenberg).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Delicious Delicious   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Expressiveness of global coagulation parameters in dilutional coagulopathy
Weiss et al.
Br J Anaesth 2010;105:429-436.
ABSTRACT | FULL TEXT  

Finding the optimal concentration range for fibrinogen replacement after severe haemodilution: an in vitro model
Bolliger et al.
Br J Anaesth 2009;102:793-799.
ABSTRACT | FULL TEXT  

Guidelines for radiologically guided lung biopsy
Manhire et al.
Thorax 2003;58:920-936.
FULL TEXT  

Screening for the Risk for Bleeding or Thrombosis
Eckman et al.
ANN INTERN MED 2003;138:W-15-W-24.
ABSTRACT | FULL TEXT  

Partial Thromboplastin Time: Prediction of Adverse Events and Poor Prognosis by Low Abnormal Values
Reddy et al.
Arch Intern Med 1999;159:2706-2710.
ABSTRACT | FULL TEXT  

Complications of Tonsillectomy and Adenoidectomy
Randall and Hoffer
Otolaryngol Head Neck Surg 1998;118:61-68.
ABSTRACT | FULL TEXT  

Value of Preoperative Prothrombin Time/Partial Thromboplastin Time as a Predictor of Postoperative Hemorrhage in Pediatric Patients Undergoing Tonsillectomy
Howells et al.
Otolaryngol Head Neck Surg 1997;117:628-632.
ABSTRACT | FULL TEXT  

How Much Routine Preoperative Laboratory Testing Is Enough?
Velanovich
American Journal of Medical Quality 1993;8:145-151.
ABSTRACT  

Routine Use of the Prothrombin and Partial Thromboplastin Times
Erban et al.
JAMA 1989;262:2428-2432.
ABSTRACT  

Evaluation of an Intervention Aimed at Reducing Inappropriate Use of Preoperative Blood Coagulation Tests
Mozes et al.
Arch Intern Med 1989;149:1836-1838.
ABSTRACT  

Changing Physician Test Ordering in a University Hospital: An Intervention of Physician Participation, Explicit Criteria, and Feedback
Spiegel et al.
Arch Intern Med 1989;149:549-553.
ABSTRACT  

The Value of Preoperative Screening Investigations in Otherwise Healthy Individuals
Turnbull and Buck
Arch Intern Med 1987;147:1101-1105.
ABSTRACT  

How Well Does the Activated Partial Thromboplastin Time Predict Postoperative Hemorrhage?
Suchman and Mushlin
JAMA 1986;256:750-753.
ABSTRACT  

Diagnostic Decision: Diagnostic Uses of the Activated Partial Thromboplastin Time and Prothrombin Time
SUCHMAN and GRINER
ANN INTERN MED 1986;104:810-816.
ABSTRACT  

The Usefulness of Preoperative Laboratory Screening
Kaplan et al.
JAMA 1985;253:3576-3581.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | PHYSICIAN JOBS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1982 American Medical Association. All Rights Reserved.