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  Vol. 117 No. 2, February 1982 TABLE OF CONTENTS
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Single-Dose Intraoperative Antibiotic Prophylaxis in Emergency Abdominal Surgery

Brian J. Rowlands, MD, FRCS; Ronald G. Clark, FRCS; David G. Richards, FRCS

Arch Surg. 1982;117(2):195-199.


Abstract

• In a randomized controlled trial of the use of a single intravenous dose of gentamicin sulfate and clindamycin phosphate used intraoperatively during emergency abdominal surgery, the overall incidence of postoperative wound infection was reduced from 32.3% to 10.4%. Significant reduction in wound infection occurred in the study group compared with control subjects, irrespective of the underlying pathologic lesion. No side effects of the use of antibiotics were noted. The policy of antibiotic prophylaxis in emergency surgery seems to be of particular benefit in elderly patients.

(Arch Surg 1982;117:195-199)



Author Affiliations

From the University Surgical Unit, Northern General Hospital, Sheffield, England. Dr Rowlands is now with the University of Texas Health Science Center, Houston.


Footnotes

Accepted for publication Sept 22, 1981.

Read at the first annual meeting of the Surgical Infection Society, Chicago, April 25, 1981.

Reprint requests to Department of Surgery, University of Texas Health Science Center, 6431 Fannin, Houston, TX 77030 (Dr Rowlands).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

A Comparison of the Roles of Cefamandole and Ceftriaxone in Abdominal Surgery
Hall et al.
Arch Surg 1991;126:512-516.
ABSTRACT  

Acute Nonperforating Appendicitis: Efficacy of Brief Antibiotic Prophylaxis
Winslow et al.
Arch Surg 1983;118:651-655.
ABSTRACT  





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