The changing pattern of hemolytic streptococcal gangrene
D. R. Aitken, M. C. Mackett and L. L. Smith
We reviewed nine cases in which either limg-threatening or life-threatening
complications developed due to streptococcal infection. Our findings
indicate important changes in the pattern of this fulminating illness since
its original description in 1924. A higher mortality reflects increased
longevity with a greater frequency of impaired host resistance and
degenerative diseases involving vital organs. Initial symptoms and signs
often mimic acute thrombophlebitis, acute arthritis, deep soft-tissue
trauma, or acute vascular occlusion. The emergence of multiple organ
failure and serious coagulation disorders are a challenge to current
therapy. A diagnostic algorithm was developed to aid in the early diagnosis
and management of this life-threatening infection.
