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Delmar R. Aitken, MD; M. C. Theodore Mackett, MD; Louis L. Smith, MD

Arch Surg. 1982;117(5):561-567.

Abstract
• We reviewed nine cases in which either limb-threatening or life-threatening complications developed due to streptococcal infection. Our findings indicate important changes in the pattern of this fulminating illness since its original description in 1924. A higher mortality reflects increased longevity with a greater frequency of impaired host resistance and degenerative diseases involving vital organs. Initial symptoms and signs often mimic acute thrombophlebitis, acute arthritis, deep soft-tissue trauma, or acute vascular occlusion. The emergence of multiple organ failure and serious coagulation disorders are a challenge to current therapy. A diagnostic algorithm was developed to aid in the early diagnosis and management of this life-threatening infection.

(Arch Surg 1982;117:561-567)

Author Affiliations
From the Department of Surgery, Loma Linda (Calif) University School of Medicine.

Footnotes
Accepted for publication Dec 28, 1981.

Read at the 89th annual meeting of the Western Surgical Association, Albuquerque, Nov 16, 1981.

Reprint requests to Department of Surgery, Loma Linda University School of Medicine, Loma Linda, CA 92354 (Dr Smith).

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