Chemotherapy before and after mastectomy in stage III breast cancer
M. Perloff and G. J. Lesnick
Seventeen patients with stage III breast cancer were treated by modified
radical mastectomy preceded and followed by multiagent cytotoxic
chemotherapy. The preoperative treatment resulted in a decrease in size of
the primary tumor, facilitating the subsequent surgical procedure. There
were no serious surgical complications. Wound healing was uneventful.
Median disease-free survival time was 29 months and median survival time
was 40+ months. Six of the 17 patients are living free of recurrence from
more than 33 to more than 79 months after initial therapy.
