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Kathie M. Dalessandri, MD; Stanley N. Carson, MD; Phillip Tillman, DVM; Linda Talken; Hin-Nang Wong, MD

Arch Surg. 1983;118(10):1157-1160.

Abstract
• We developed a model that simulates distal arterial occlusive disease to determine the effects of sympathectomy on certain hemodynamic changes. Two groups of seven dogs each received unilateral distal popliteal artery ligation. intraarterial BPs, angiography, pulse volume recordings (PVRs), and photoplethysmograms were taken of the distal hind limb throughout the experiment. After ligation, PVR and distal hind limb pressures were lowered to less than half of the preligation values. Four days after unilateral distal popliteal artery ligation, group 2 dogs received lumbar sympathectomy on the same side as the ligation. One week after sympathectomy, the PVR amplitudes and pressures showed a transient significant rise. Two weeks after sympathectomy, the PVR pressures and amplitudes returned to the previous, diminished postligation values.

(Arch Surg 1983;118:1157-1160)

Author Affiliations
From the Department of Surgery, Vascular Surgery Section, Veterans Administration Medical Center, Martinez, Calif (Drs Dalessandri, Carson, and Wong) and the Animal Resource Service, School of Veterinary Medicine, University of California, Davis (Dr Tillman and Ms Talken).

Footnotes
Accepted for publication March 30, 1983.

Read before the Fifth Annual Surgical Symposium of Veterans Administration Surgeons, Minneapolis, May 13, 1981.

Reprint requests to Department of Surgery (112), VA Medical Center, Martinez, CA 94553 (Dr Dalessandri).

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