This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (86)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Kenneth W. Burchard, MD; Lloyd B. Minor, MD; Gus J. Slotman, MD; Donald S. Gann, MD

Arch Surg. 1983;118(2):217-221.

Abstract
• Records of 65 surgical patients with positive fungal blood cultures were reviewed to address risk, overall mortality, and treatment. Negative urine cultures did not rule out sepsis. Staphylococcus epidermidis sepsis was present in 27 (42%) of the patients, in 70% of whom it occured before or during fungemia. Increased mortality correlated with the use of multiple antibiotics, antibiotic use for prolonged periods, and with associated bacterial sepsis. Stopping antibiotic therapy did not reduce mortality. Amphotericin B reduced mortality in patients with dissemination, indicating that it is the treatment of choice for disseminated fungemia and that antibiotic therapy should not be discontinued when concomitant bacterial sepsis is present.

(Arch Surg 1983;118:217-221)

Author Affiliations
From the Department of Surgery, Rhode Island Hospital, Providence.

Footnotes
Accepted for publication Sept 16, 1982.

Read before the second annual meeting of the Surgical Infection Society, Boston, April 20, 1982.

Reprint requests to Department of Surgery, Rhode Island Hospital, 593 Eddy St, Providence, RI 02902 (Dr Burchard).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Effect of Empiric and Prophylactic Treatment With Fluconazole on Yeast Isolates in a Surgical Trauma Intensive Care Unit
Safran and Dawson
Arch Surg 1997;132:1184-1189.
ABSTRACT  

Emerging and Reemerging Microbial Threats: Nosocomial Fungal Infections
Henderson and Hirvela
Arch Surg 1996;131:330-337.
ABSTRACT  

Prognostic Indicators in Fungemia of the Surgical Patient
Tang et al.
Arch Surg 1993;128:759-763.
ABSTRACT  

Clinical Spectrum of Fungal Infections After Orthotopic Liver Transplantation
Castaldo et al.
Arch Surg 1991;126:149-156.
ABSTRACT  

Pathogenesis of Candidiasis: Immunosuppression by Cell Wall Mannan Catabolites
Podzorski et al.
Arch Surg 1989;124:1290-1294.
ABSTRACT  

Hospital-Acquired Candidemia: The Attributable Mortality and Excess Length of Stay
Wey et al.
Arch Intern Med 1988;148:2642-2645.
ABSTRACT  

Ketoconazole Prevents Candida Sepsis in Critically Ill Surgical Patients
Slotman and Burchard
Arch Surg 1987;122:147-151.
ABSTRACT  

Candida Sepsis: Implications of Polymicrobial Blood-Borne Infection
Dyess et al.
Arch Surg 1985;120:345-348.
ABSTRACT  

Enterococcal Bacteremia in Surgical Patients
Barrall et al.
Arch Surg 1985;120:57-63.
ABSTRACT  

Staphylococcus epidermidis Sepsis in Surgical Patients
Burchard et al.
Arch Surg 1984;119:96-100.
ABSTRACT