Prognosis in generalized peritonitis. Relation to cause and risk factors
J. Bohnen, M. Boulanger, J. L. Meakins and A. P. McLean
Generalized peritonitis was assessed in 176 patients, 67 (38%) of whom
died. Cases were divided into causative groups: (1) appendicitis and
perforated duodenal ulcer, (2) intraperitoneal origin other than appendix
or duodenum, and (3) postoperative peritonitis. Mortalities were 10%, 50%,
and 60%, respectively. Postoperative peritonitis was characterized by lack
of influence of age on outcome, late operation, and more frequent organ
failure. Delayed surgery carried a worse prognosis. Organ failure was a
risk factor with 76% mortality, and was associated with late operation.
Early surgery in organ failure improved survival. More sensitive indicators
of early organ dysfunction might improve survival.
