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Relation to Cause and Risk Factors

John Bohnen, MD, FRCS(C); Micheline Boulanger, RN; Jonathan L. Meakins, MD, DSc, FRCS(C); A. Peter H. McLean, MD, FRCS(C)

Arch Surg. 1983;118(3):285-290.

Abstract
• Generalized peritonitis was assessed in 176 patients, 67 (38%) of whom died. Cases were divided into causative groups: (1) appendicitis and perforated duodenal ulcer, (2) intraperitoneal origin other than appendix or duodenum, and (3) postoperative peritonitis. Mortalities were 10%, 50%, and 60%, respectively. Postoperative peritonitis was characterized by lack of influence of age on outcome, late operation, and more frequent organ failure. Delayed surgery carried a worse prognosis. Organ failure was a risk factor with 76% mortality, and was associated with late operation. Early surgery in organ failure improved survival. More sensitive indicators of early organ dysfunction might improve survival.

(Arch Surg 1983;118:285-290)

Author Affiliations
From the Departments of Surgery (Drs Bohnen, Meakins, and McLean and Ms Boulanger) and Microbiology (Dr Meakins), Royal Victoria Hospital, McGill University, Montreal.

Footnotes
Accepted for publication Sept 20, 1982.

Read before the second annual meeting of the Surgical Infection Society, Boston, April 20, 1982.

Reprint requests to Royal Victoria Hospital, 687 Pine Ave W, Room S10.30, Montreal, Quebec, Canada H3A 1A1 (Dr Meakins).

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