 |
|
Acquired Immune Deficiency SyndromeA Surgical Perspective
John M. Davis, MD;
Janet Mouradian, MD;
Richard D. Fernandez, MD;
Susanna Cunningham-Rundles, PhD;
Craig E. Metroka, MD, PhD
Arch Surg. 1984;119(1):90-95.
Abstract
• Eighty-nine lymph node biopsies were performed on 82 patients with lymphadenopathy, immunosuppression, and possible acquired immune deficiency syndrome. The 21 patients with diagnoses of lymphoma or Kaposi's sarcoma were older, had more sexual contacts, and were sexually active for more years than patients with benign diagnoses. Cytomegalovirus and Epstein-Barr viral titers were elevated in both groups but were not significantly different in the benign and malignant groups. Skin flora were cultured from lymph node tissue in 24.7% of the patients. Two patients (2.5%) had wound infections with the same bacterium present in the lymph node culture, while 66 patients initially had two different benign pathologic patterns. Fifty-six patients had explosive follicular hyperplasia, and ten had follicular involution. Four of the patients with follicular involution and one with follicular hyperplasia subsequently had malignant tumors.
(Arch Surg 1984;119:90-95)
Author Affiliations
From the Departments of Surgery (Dr Davis), Pathology (Drs Mouradian and Fernandez), and Medicine, Hematology Division (Dr Metroka), Cornell University Medical College, and the Department of Clinical Immunology and Human Immunogenetics (Dr Cunningham-Rundles), Memorial SloanKettering Cancer Center, New York.
Footnotes
Accepted for publication Sept 14, 1983.
Read before the Third Annual Meeting of the Surgical Infection Society, Fort Lauderdale, Fla, May 9, 1983.
Reprint requests to Department of Surgery, Cornell University Medical College, 1300 York Ave, New York, NY 10021 (Dr Davis).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Lymph Node Biopsy in Patients With Human Immunodeficiency Virus Infections
Davis et al.
Arch Surg 1988;123:1349-1352.
ABSTRACT
|
