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Carl J. Hauser, MD; Stanley R. Klein, MD; C. Mark Mehringer, MD; Paul Appel, MPA; William C. Shoemaker, MD

Arch Surg. 1984;119(6):690-694.

Abstract
• Transcutaneous oxygen tension P_tco² is directly related to skin oxygen delivery. Regional transcutaneous oximetry (RTO) compares peripheral and truncal (P_tcO₂)3 yielding a regional perfusion index indicative of local limb perfusion. The relative diagnostic values of RTO, Doppler ankle-brachial pressure ratio (ABR), pulse volume recording (PVR), and toe pulse reappearance time (PRT/2) were studied in 64 limbs of patients with diabetes. These limbs were clinically classifiable into claudication, rest pain, and gangrene groups. Regional transcutaneous oximetry had a higher diagnostic accuracy than ABR (² = 27.47, P<.001), PVR (² = 7.54, P <.01), and PRT/2 (²=10.99, P<.001). Regional transcutaneous oximetry was universally applicable and the degree of hypoxia observed correlated with clinical symptoms. Significant hypoxia predicted large-vessel angiographic lesions, many of which were reconstructible. Regional transcutaneous oximetry should be the initial noninvasive test in diabetic peripheral vascular disease.

(Arch Surg 1984;119:690-694)

Author Affiliations
From the Departments of Surgery (Drs Hauser, Klein, Appel, Shoemaker) and Radiology (Dr Mehringer), Harbor/UCLA Medical Center, Torrance, Calif.

Footnotes
Accepted for publication Feb 8, 1984.

Read before the 91st annual meeting of the Western Surgical Association, Monterey, Calif, Nov 15, 1983.

Reprint requests to Harbor/UCLA Medical Center, 1000 W Carson St, Torrance, CA 90509 (Dr Hauser).

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