 |
|
Perfluorocarbon Infusion in Bleeding Patients Refusing Blood Transfusions
Kenneth Waxman, MD;
Kevin K. Tremper, PhD, MD;
Bruce F. Cullen, MD;
G. Robert Mason, MD, PhD
Arch Surg. 1984;119(6):721-724.
Abstract
• Six severely anemic surgical patients who refused blood products were treated with a perfluorochemical (PFC) emulsion (Fluosol-DA 20%). When these patients received high inspired oxygen concentrations, the emulsion resulted in moderate increases of arterial oxygen content but considerable increases of oxygen consumption, suggesting improved microcirculatory oxygen distribution. The mean ± SD percentages of consumed oxygen transported by dissolved oxygen in PFC and PFC plus plasma emulsions were 22%±5% and 60% ±12%, respectively. Several adverse clinical effects were seen, however, including transient decreases in leukocyte counts, hypotension, and abnormal hepatic and pulmonary function.
(Arch Surg 1984;119:721-724)
Author Affiliations
From the Departments of Surgery (Drs Waxman and Mason) and Anesthesiology (Drs Tremper and Cullen), University of California at Irvine, Orange.
Footnotes
Accepted for publication Dec 28, 1983.
Read before the 91st annual meeting of the Western Surgical Association, Monterey, Calif, Nov 16, 1983.
Reprint requests to Department of Surgery, University of California—Irvine Medical Center, 101 City Dr S, Orange, CA 92668 (Dr Waxman).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Fluorocarbon emulsions
Marchbank
Perfusion 1995;10:67-88.
Management of the Severely Anemic Patient Who Refuses Transfusion: Lessons Learned during the Care of a Jehovah's Witness
Mann et al.
ANN INTERN MED 1992;117:1042-1048.
ABSTRACT
|
