This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Reduction of Wound Sepsis Following Emergency Appendectomy

David J. Sherlock, FRCS; Anthony Ward, FRCS; Robert T. J. Holl-Allen, MS, FRCS, FACS

Arch Surg. 1984;119(8):909-911.

Abstract
• Single doses of clindamycin hydrochloride and gentamicin sulfate given preoperatively, combined with intraoperative topical application of povidone-iodine were given to patients with perforated or gangrenous appendicitis. The incidence of wound sepsis was reduced from 36% to 5%; severe infections were reduced from 25% to 0% when compared with a control untreated group of patients. When used alone, povidone-iodine had little effect in these patients. No toxic effects of the antibiotics or antiseptic were recorded nor were any resistant strains of pathogenic organisms grown from cultures.

(Arch Surg 1984;119:909-911)

Author Affiliations
From the Department of Surgery, East Birmingham Hospital, England.

Footnotes
Accepted for publication March 27, 1984.

Reprint requests to Department of Surgery, East Birmingham Hospital, Bordesley Green East, B9 5ST Birmingham, England (Dr Holl-Allen).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?