This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (57)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Helen M. Shaw, PhD; Craig W. Beattie, PhD; William H. McCarthy, FRACS, MEd; Gerald W. Milton, FRCS, FRACS

Arch Surg. 1985;120(10):1155-1159.

Abstract
• In 1,283 patients with cutaneous stage I malignant melanoma who had ten or more years of follow-up, the incidence of late recurrence (first evidence of metastases occurring ten or more years after melanoma diagnosis) was 2.7%. None of the factors of prognostic importance (anatomic site, tumor thickness, ulcerative state of primary lesion, or initial surgical treatment) proved useful in predicting those patients with late recurrence. There was no sex or age difference in either incidence of late recurrence or prognosis subsequent to recurrence. Prognosis subsequent to late recurrence depended on the site of the recurrence. Survival after distant metastases became evident was extremely short. However, in the majority (53%) of patients, late recurrence was local and survival subsequent to treatment of these metastases was often protracted, emphasizing the importance of long-term follow-up in all patients with cutaneous melanoma.

(Arch Surg 1985;120:1155-1159)

Author Affiliations
From the Sydney Melanoma Unit, Department of Surgery, University of Sydney, Camperdown, Australia (Dr Shaw and Professors McCarthy and Milton); and the Division of Surgical Oncology, University of Illinois School of Medicine, Chicago (Dr Beattie).

Footnotes
Accepted for publication May 7, 1985.

Reprint requests to Sydney Melanoma Unit, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Australia (Dr Shaw).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Circulating Tumor Cells in Patients with Breast Cancer Dormancy
Meng et al.
Clin. Cancer Res. 2004;10:8152-8162.
ABSTRACT | FULL TEXT  

Detection and characterization of carcinoma cells in the blood
Racila et al.
Proc. Natl. Acad. Sci. USA 1998;95:4589-4594.
ABSTRACT | FULL TEXT  

Recurrence Patterns and Outcome in 1019 Patients Undergoing Axillary or Inguinal Lymphadenectomy for Melanoma
Gadd and Coit
Arch Surg 1992;127:1412-1416.
ABSTRACT  

Prognosis After Initial Recurrence of Cutaneous Melanoma
Markowitz et al.
Arch Surg 1991;126:703-708.
ABSTRACT  

Serial Determinations of Melanoma Tumor--Associated Antigen and Antibody in Patients With Stage I Melanoma
Wong et al.
Arch Surg 1986;121:1342-1345.
ABSTRACT  

Prognosis in Melanoma: What Have We Learned?
Koh
Arch Dermatol 1986;122:993-994.
ABSTRACT