Early somatostatinoma of the papilla of the duct of Santorini
M. J. Malone, M. L. Silverman, J. W. Braasch, G. L. Jin and Y. Dayal
We studied a patient with a very small somatostatinoma that arose from the
prominence of the orifice of the duct of Santorini. The patient presented
clinically with epigastric discomfort, marked loss of weight, diarrhea,
exertional dyspnea, and chest pain. He flushed intermittently and had
occasional tachycardia and hypertension. Levels of serum serotonin and
urinary 5-hydroxyindoleacetic acid were normal. A small ampullary tumor was
resected and identified by immunohistochemical staining to be a
somatostatinoma. The patient had gained 6.75 kg and was essentially free of
symptoms 16 months after surgery.
