You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


Advertisement

ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | RSS | Access Rights | Sign In


  Vol. 120 No. 4, April 1985 TABLE OF CONTENTS
  Online Only
 •  Online First Table of
Contents
  ORIGINAL ARTICLES
 •Online Features
 This Article
 •References
 •Full text PDF
 • Reply to article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Citing articles on Web of Science (71)
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Delicious Add to Digg Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this?

An Objective Assessment of the Physiologic Changes in the Postthrombotic Syndrome

Lois A. Killewich, MD, PhD; Robert Martin; Miles Cramer; Kirk W. Beach, MD, PhD; D. E. Strandness, Jr, MD

Arch Surg. 1985;120(4):424-426.


Abstract



• To determine what physiologic changes might contribute to the development of the postthrombotic syndrome, venous outflow, venous refilling time, and valvular competence were assessed in 32 patients (39 limbs) with documented deep venous thrombosis. The follow-up ranged from nine to 144 months (mean, 41 months) after the acute deep venous thrombosis. Pain was noted by 49% of the patients, but more objective end points occurred less frequently (edema, 21%; pigmentation, 26%; ulceration, 3%). Venous outflow was lower in the affected limbs but was not a good indicator of those patients with or without symptoms. Venous refilling time after calf compression was markedly reduced in limbs with incompetent valves (mean ± SD, 8.4 ± 3.8 s v 25.3 ±12.1 s), as well as in those with edema, pigmentation, and ulceration. It appears that most of the sequelae of the postthrombotic syndrome can be attributed to the loss of valvular function.

(Arch Surg 1985;120:424-426)



Author Affiliations



From the Department of Surgery, University of Washington School of Medicine, Seattle.


Footnotes



Accepted for publication Sept 12, 1984.

Reprint requests to Department of Surgery, RF-25, University of Washington, Seattle, WA 98195 (Dr Strandness).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Delicious Delicious   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Incidence and risk factors of the post-thrombotic syndrome
de Wolf et al.
Phlebology 2012;27:85-94.
ABSTRACT | FULL TEXT  

Catheter-Directed Thrombectomy and Thrombolysis for Symptomatic Lower-Extremity Deep Vein Thrombosis: Review of Current Interventional Treatment Strategies
Lin et al.
PERSPECT VASC SURG ENDOVASC THER 2010;22:152-163.
ABSTRACT  

Thromboembolism: Reducing maternal death and disability during pregnancy
Drife
Br Med Bull 2003;67:177-190.
ABSTRACT | FULL TEXT  

Investigation of Chronic Venous Insufficiency : A Consensus Statement
Nicolaides
Circulation 2000;102:e126-e163.
ABSTRACT | FULL TEXT  

Thrombolytic Therapy for Deep Venous Thrombosis?
Horne III and Chang
JAMA 1999;282:2164-2166.
ABSTRACT | FULL TEXT  

Clinical Correlation to Various Patterns of Reflux
Labropoulos
VASC ENDOVASCULAR SURG 1997;31:242-248.
 

Acute DVT: Long-Term Results of Conservative Treatment
Strandness
VASC ENDOVASCULAR SURG 1997;31:309-311.
 

A Comparison of the Cuff Deflation Method With Valsalva's Maneuver and Limb Compression in Detecting Venous Valvular Reflux
Markel et al.
Arch Surg 1994;129:701-705.
ABSTRACT  

Surgical treatment of the postphlebitic limb
McMullin
Vasc Med 1990;1:69-83.
 

Streptokinase vs Heparin for Deep Venous Thrombosis: Can Lytic Therapy Be Justified?
Sidorov
Arch Intern Med 1989;149:1841-1845.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | PHYSICIAN JOBS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1985 American Medical Association. All Rights Reserved.