This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Bonnie L. Beaver, MD; Donn Young, PhD; Bhagwan Satiani, MB, BS

Arch Surg. 1985;120(4):436-438.

Abstract
• It has been suggested that early heparin requirements are greater in patients with acute deep venous thrombosis (DVT) and pulmonary embolism (PE). Heparin requirements were recorded for 73 patients with suspected DVT and PE. The maintenance dosage (days 1 through 4) of heparin sodium required to achieve therapeutic partial thromboplastin times (PTTs) was significantly higher in patients with DVT (n=54; mean ± SD dosage, 1,151±246 units/hr) compared with patients with no DVT (n=19; mean± SD dosage, 952±190 units/ hr). The first posttreatment PTT was significantly lower in patients with DVT (mean ± SD PTT, 68.74± 27.96 s) compared with control patients (mean ± SD PTT, 89.41±23.25 s). This study supports the clinical impression that initial heparin requirements are greater and heparin clearance is more rapid in patients with acute DVT and PE.

(Arch Surg 1985;120:436-438)

Author Affiliations
From the Departments of Surgery, Grant Hospital (Drs Beaver and Satiani) and Ohio State University (Drs Beaver, Satiani and Young), Columbus.

Footnotes
Accepted for publication Nov 28, 1984.

Reprint requests to 300 E Town St, Suite 613, Columbus, OH 43215 (Dr Satiani).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?