You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 120 No. 5, May 1985 TABLE OF CONTENTS
  Archives
  •  Online Features
  PAPERS READ BEFORE THE 92ND ANNUAL MEETING OF THE WESTERN SURGICAL ASSOCIATION, COLORADO SPRINGS, COLO, NOV 12-14, 1984-PART I
 This Article
 •References
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Surgical Management of Hyperinsulinism in the Multiple Endocrine Neoplasia, Type 1 Syndrome

Dennis A. Rasbach, MD; Jon A. van Heerden, MB, FRCS(C); Robert L. Telander, MD; Clive S. Grant, MD; J. Aidan Carney, MD

Arch Surg. 1985;120(5):584-589.


Abstract

• We retrospectively reviewed the records of 12 patients from one institution (from 1970 through 1983) who had hyperinsulinism as a part of the multiple endocrine neoplasia, type 1 syndrome. All of the patients underwent surgical exploration: ten had subtotal pancreatectomies, one had enucleation, and one underwent a total pancreatectomy. There was no operative mortality. Preoperative and intraoperative localization studies (angiography and ultrasonography) tended to underestimate the number of pancreatic tumors. Ten patients had multiple B-cell adenomas (mean, 7.4), while two patients had single tumors. This study confirms that hyperinsulinism, when it occurs as part of the multiple endocrine neoplasia, type 1 syndrome, is usually due to multiple islet cell tumors, and that the islet cell tissue is probably diffusely dysplastic. Subtotal (85%) pancreatectomy is suggested as the procedure of choice for this subgroup of patients with hyperinsulinism.

(Arch Surg 1985;120:584-589)



Author Affiliations

From the Departments of Surgery (Drs Rasbach, van Heerden, Telander, and Grant) and Pathology (Dr Carney), Mayo Clinic and Mayo Foundation, Rochester, Minn. Dr Rasbach is a visiting clinician from the Milton S. Hershey Medical Center, Hershey, Pa.


Footnotes

Accepted for publication Feb 5, 1985.

Read before the 92nd annual meeting of the Western Surgical Association, Colorado Springs, Colo, Nov 13, 1984.

Reprint requests to Department of Surgery, Mayo Clinic, Rochester, MN 55905 (Dr van Heerden).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Rapid Intraoperative Immunoassay of Parathyroid Hormone and Other Hormones: A New Paradigm for Point-of-Care Testing
Sokoll et al.
Clin. Chem. 2004;50:1126-1135.
ABSTRACT | FULL TEXT  

Insulinoma: The Value of Intraoperative Ultrasonography
Grant et al.
Arch Surg 1988;123:843-848.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1985 American Medical Association. All Rights Reserved.