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Experience With Red Blood Cells Labeled In Vitro With Technetium Tc 99m

MAJ Paul M. Orecchia, MC; CPT Edward K. Hensley, MC; COL Paul T. McDonald, MC; COL Robert J. Lull, MC

Arch Surg. 1985;120(5):621-624.

Abstract
• Seventy-six patients clinically suspected of having lower gastrointestinal bleeding were studied by scintigraphy utilizing red blood cells labeled in vitro with technetium Tc 99m. Sixteen patients required emergency surgery; bleeding was accurately localized in 15 (94%). One patient (6%) had a normal scan. A 20-month mean follow-up of the 16 patients showed no recurrent bleeding. Of 60 patients not requiring emergency surgery, bleeding was localized in 11, but the bleeding ceased. Forty-nine of the 60 patients had normal scans and had no further hemorrhaging during hospitalization. A 21-month mean follow-up of 38 of the 49 patients showed no further bleeding episodes or surgical procedures in 29 patients; however, eight patients required surgical procedures, including seven for gastrointestinal malignancies. Scanning of red blood cells labeled in vitro with ^99mTc is accurate and efficacious in localization of bleeding sites that require emergency surgery for lower gastrointestinal hemorrhage.

(Arch Surg 1985;120:621-624)

Author Affiliations
USA; USA; USA; USA

From the General Surgery Service, Department of Surgery (Drs Orecchia, Hensley, and McDonald), and the Nuclear Medicine Service, Department of Radiology (Dr Lull), Letterman Army Medical Center, Presidio of San Francisco.

Footnotes
Accepted for publication Feb 11, 1985.

Read before the 92nd annual meeting of the Western Surgical Association, Colorado Springs, Colo, Nov 13, 1984.

The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.

Reprint requests to Letterman Army Medical Center, Presidio of San Francisco, CA 94129-6700 (Technical Publications Editor).

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