This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (29)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Alan R. Shons, MD, PhD; Donald G. McQuarrie, MD, PhD

Arch Surg. 1985;120(9):1007-1009.

Abstract
• In a series of 405 patients with epidermoid carcinoma of the head and neck, 52 patients (13%) developed multiple epidermoid carcinomas of the upper aerodigestive tract. Subsequent primary tumors developed with nearly equal frequency in the head and neck, lung, and esophagus. Forty of the patients developed a subsequent primary carcinoma within five years of the first. Thirty-eight (73%) of the patients who developed a subsequent primary carcinoma survived less than two years from its diagnosis. The majority (34/50) of the patients died from the subsequent primary carcinoma. We recommend that panendoscopy and an esophagogram be performed on initial evaluation of patients with head and neck cancer. A thorough reexamination is warranted if new symptoms or signs develop.

(Arch Surg 1985;120:1007-1009)

Author Affiliations
From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Minnesota Hospitals (Dr Shons), and the Department of Surgery, Veterans Administration Hospital (Dr McQuarrie), Minneapolis. Dr Shons is now with University Hospitals, Cleveland.

Footnotes
Accepted for publication March 27, 1985.

Reprint requests to Division of Plastic and Reconstructive Surgery, University Hospitals, 2074 Abington Rd, Cleveland, OH 44106 (Dr Shons).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Synchronous and Metachronous Squamous Cell Carcinomas of the Head and Neck Mucosal Sites
Erkal et al.
JCO 2001;19:1358-1362.
ABSTRACT | FULL TEXT  

Multiple Primary Cancers in Esophageal Squamous Cell Carcinoma: Incidence and Implications
Poon et al.
Ann. Thorac. Surg. 1998;65:1529-1534.
ABSTRACT | FULL TEXT  

Esophagography and Esophagoscopy: Comparison in the Examination of Patients With Head and Neck Carcinoma
Nino-Murcia et al.
Arch Otolaryngol Head Neck Surg 1990;116:917-919.
ABSTRACT  

Toluidine Blue Staining of the Esophagus: A Useful Adjunct in the Panendoscopic Evaluation of Patients With Squamous Cell Carcinoma of the Head and Neck
Hix and Wilson
Arch Otolaryngol Head Neck Surg 1987;113:864-865.
ABSTRACT