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Lucy Wortham James Clinical Research Award

Arthur G. James, MD

Arch Surg. 1986;121(11):1233-1236.

Abstract
• Some of the breast cancer chemotherapy trials conducted during the past 25 years were reviewed. In general, most authors noted a significantly improved disease-free survival and overall survival in premenopausal patients but not in postmenopausal patients. Considering all patients, most authors found a significant increase in the disease-free survival but not in overall survival. In one study, the relapse rate increased with time. In the first three years, the relapse rate in the control group greatly exceeded that in the treatment group, but as the years went on, this trend reversed, and an increasing percentage of the treated group had relapse. More time is required to draw firm conclusions.

(Arch Surg 1986;121:1233-1236)

Author Affiliations
From The Ohio State University Cancer Hospital and Research Institute, and the Department of Surgery, Ohio State University College of Medicine, Columbus.

Footnotes
Accepted for publication July 31, 1986.

Read before the 39th Annual Meeting of the Society of Surgical Oncology, Washington, DC, May 12, 1986.

Reprint requests to the Medical Director, Room N-724, Doan Hall, 410 W Tenth Ave, Columbus, OH 43210 (Dr James).

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