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The James Ewing Lecture

Harvey W. Baker, MD

Arch Surg. 1986;121(11):1237-1241.

Abstract
• There is abundant clinical and laboratory evidence that host defenses are a significant factor in the progression and the control of cancer. The host immune system plays the major role, primarily through cell-mediated responses to the neoplastic threat. Great progress has been made in evaluating immune competence, although the specific defects have not been identified in all patients. The history of immunotherapy includes numerous trials, with few successes and many failures. Advances in knowledge and technology, however, indicate that efforts to manipulate and strengthen host defenses have great potential in the fight against cancer.

(Arch Surg 1986;121:1237-1241)

Author Affiliations
From the Department of Surgery, Oregon Health Sciences University, Portland.

Footnotes
Accepted for publication Aug 11, 1986.

Read before the 39th Annual Meeting of the Society of Surgical Oncology, Washington, DC, May 14, 1986.

Reprint requests to 1015 NW 22nd St, Portland, OR 97210 (Dr Baker).

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