One-stage simple mastectomy with immediate reconstruction for high-risk patients. An improved technique: the biologic basis for ductal-glandular mastectomy
K. I. Bland, B. O'Neal, L. J. Weiner and G. R. Tobin 2nd
The heterogeneity of human breast carcinoma appears to be a cumulative
interrelationship of genetic and environmental factors that may be
identifiable with a high risk for carcinogenesis. Until breast cancer
prevention is realized, one-stage total ductal-glandular mastectomy with
immediate reconstruction may be offered as an alternative to simple
mastectomy for women at high risk for developing cancer. This technique
affords the complete extirpation of breast tissue at a deep plane with
flaps that are identical in thickness to those elevated in classic
mastectomies for invasive cancer. Breast reconstruction with submuscular
prostheses in a one-stage procedure gives an aesthetically acceptable
result. The role of ductal-glandular mastectomy as prophylaxis for invasive
carcinoma warrants future prospective trials.