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Pulmonary Dysfunction Associated With Streptokinase Therapy
Morris D. Kerstein, MD;
Michael F. Adinolfi, MD
Arch Surg. 1986;121(7):852-853.
Abstract
A 66-year-old lower-extremity amputee with an acute femoral artery occlusion was treated with low-dose (10 000 units/h) percutaneous constant-infusion streptokinase. At 48 hours after initiation of therapy, the patient experienced adult respiratory distress syndrome and died. A postmortem examination confirmed the diagnosis; laboratory studies reflected an increased level of fibrinolytic split products, thrombocytopenia, and a low level of fibrinogen.
(Arch Surg 1986;121:852-853)
Author Affiliations
From the Department of Surgery, Tulane University School of Medicine, New Orleans.
Footnotes
Accepted for publication Dec 2, 1985.
Reprints not available.
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ABSTRACT
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