This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (28)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Philippe Gertsch, MD; Pierre-William Loup, MD; Alexandra Lochman, MD; Prosper Anani, MD

Arch Surg. 1986;121(9):1061-1064.

Abstract
• We report and analyze two cases of Ehlers-Danlos syndrome (EDS) type 4. The first manifestation of the disease was a spontaneous perforation of the colon in a 47-year-old man; he was successfully reoperated on five years later for the rupture of an abdominal aortic aneurysm. Abdominal pain demonstrated the syndrome in a 33-year-old woman in whom multiple abdominal aneurysms were found. A ligation of the anterior tibial artery for spontaneous rupture was performed five years later. Light and electron microscopic studies of the skin disclosed similar alterations in both cases. The diameter of the collagen fiber bundles was reduced and the diameter of collagen fibrils was increased. It appears that EDS type 4 might be less characteristic than has been previously described. Classification of the different types of EDS according to electron microscopy is not possible.

(Arch Surg 1986;121:1061-1064)

Author Affiliations
From the Surgical Service (Drs Gertsch and Loup) and Institute of Pathology (Drs Lochman and Anani), Central Hospital, Vaudois University, Lausanne, Switzerland.

Footnotes
Accepted for publication Jan 23, 1986.

Reprint requests to Service dei chirurgie B, 1011 Lausanne-CHUV, Switzerland (Dr Gertsch).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Survival after spontaneous aortic rupture in a patient with Ehlers-Danlos syndrome
Dambrin et al.
Eur. J. Cardiothorac. Surg. 2005;28:650-652.
ABSTRACT | FULL TEXT