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Carl J. Hauser, MD

Arch Surg. 1987;122(10):1128-1130.

Abstract
• Healing of both pathologic and surgical wounds is strongly dependent on adequate skin blood flow and oxygenation. The transcutaneous oxygen tension (P_tco₂) index (regional P_tco₂ index = RPI = limb P_tco₂/chest P_tco₂) and wound healing were assessed prospectively in 159 wounds in 113 high-risk patients referred for standard noninvasive tests. Patients were managed by referring practitioners on the basis of clinical assessment and standard tests. Treatment was divided into local procedures and amputations. Of 93 local procedures, 48 healed (RPI = 0.72 ± 0.10 [mean ± SD] and 45 failed (RPI = 0.25 ± 0.12). Of 66 amputations, 45 healed (RPI = 0.64 ± 0.09) and 21 failed (RPI = 0.28 ± 0.11). Well-oxygenated skin healed reliably regardless of the cause of the wound. Regional skin oxygenation studies aid rapid diagnosis of ischemia and allow maximal conservation of tissue in limb salvage situations.

(Arch Surg 1987;122:1128-1130)

Author Affiliations
From the Division of Surgery, Hollywood Presbyterian Medical Center, Los Angeles.

Footnotes
Accepted for publication June 24, 1987.

Read before the Annual Scientific Meeting of the Southern California Chapter of the American College of Surgeons, Santa Barbara, Calif, Jan 16, 1987.

Reprint requests to Department of Medical Education, Hollywood Presbyterian Medical Center, 1300 N Vermont Ave, Los Angeles, CA 90027 (Kay

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