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Resting Energy Expenditure of Host and Tumor Is Similar in Rats With Methylcholanthrene-Induced Sarcoma
Herbert R. Freund, MD;
Myung Wook Kim, MD;
Michael Muggia-Sullam, MD;
William T. Chance, PhD;
Josef E. Fischer, MD
Arch Surg. 1987;122(10):1151-1152.
Abstract
In the present study we assessed the resting energy expenditure of 30 free-feeding control and methylcholanthrene-induced sarcoma-bearing rats prior to and following surgical removal of the tumor. Tumor-bearing rats demonstrated carcass wasting and massive tumor growth. The resting energy expenditure data in our model suggest that neither the presence and growth of a tumor nor its removal significantly change resting energy expenditure beyond the normal range for non—tumor-bearing rats. We suggest that in the partition of energy costs between host and tumor, both carry a similar input, proportional to their relative weight, into the total combined resting energy expenditure of host and tumor.
(Arch Surg 1987;122:1151-1152)
Author Affiliations
From the Department of Surgery, University of Cincinnati Medical Center. Drs Freund and Muggia-Sullam are now with the Hebrew University—Hadassah Medical School, Jerusalem. Dr Kim is now with the Yonsei University College of Medicine, Seoul, Korea.
Footnotes
Accepted for publication Dec 9, 1986.
Reprint requests to the Department of Surgery, University of Cincinnati Medical Center, 231 Bethesda Ave (ML #558), Cincinnati, OH 45267 (Dr Fischer).
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