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  Vol. 122 No. 11, November 1987 TABLE OF CONTENTS
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  PAPERS READ BEFORE THE ANNUAL MEETING OF THE SOCIETY OF SURGICAL ONCOLOGY, LONDON, APRIL 27 TO APRIL 30, 1987-PART I
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Challenges in the Treatment of Childhood Fibromatosis

Bhaskar N. Rao, MD; Marc E. Horowitz, MD; David M. Parham, MD; Erlinda E. Etcubanas, MD; Irvin D. Fleming, MD; Charles B. Pratt, MD; H. Omar Hustu, MD; Alexander A. Green, MD; Larry E. Kun, MD

Arch Surg. 1987;122(11):1296-1298.


Abstract

• Between 1968 and 1985, we treated 20 children for fibromatosis (also called desmoid tumor and aggressive fibromatosis). The primary sites included head and neck (seven patients), extremity (seven patients), and trunk (six patients). Lesions ranged from 3 to 18 cm in diameter. The tumors were smaller than 5 cm in 13 patients, and in seven patients they were larger than 5 cm. A total resection was not feasible in any of the patients with lesions larger than 5 cm. Ten of the 11 patients treated with wide local resection, in whom the margins were clearly negative or close, remained free of disease for six to 16 years. Nine patients required additional treatment with radiotherapy (nine patients) and chemotherapy (five patients). Two died of local disease progression. In the remaining seven children, the disease was controlled. We describe our strategies for managing this disease in a pediatric population.

(Arch Surg 1987;122:1296-1298)



Author Affiliations

From the Divisions of Surgery (Drs Rao and Fleming), Hematology-Oncology (Drs Horowitz, Etcubanas, Pratt, and Green), Pathology (Dr Parham), and Radiation Oncology (Drs Hustu and Kun), St Jude Children's Research Hospital, and the Departments of Pediatrics (Drs Horowitz, Etcubanas, Pratt, and Green), Surgery (Drs Rao and Fleming), and Radiology (Drs Hustu and Kun), The University of Tennessee College of Medicine, Memphis.


Footnotes

Accepted for publication July 16, 1987.

Read before the Annual Meeting of the Society of Surgical Oncology, London, April 27, 1987.

Reprint requests to Division of Surgery, St Jude Children's Research Hospital, 332 N Lauderdale, Memphis, TN 38101 (Dr Rao).



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