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Peter N. Benotti, MD; Albert Bothe, Jr, MD; Robert C. Eyre, MD; Blake Cady, MD; William V. McDermott, MD; Glenn Steele, MD

Arch Surg. 1987;122(4):457-460.

Abstract
• The management of regional tumor recurrence in the pelvis traditionally has been a difficult problem for surgeons and oncologists. The only meaningful therapy for these patients is a potentially curative re-resection. The records and operative reports of 29 patients with regional pelvic tumor recurrence treated between 1981 and 1986 were reviewed. The operative procedures performed included three bowel resections, six abdominoperineal resections, eight pelvic exenterations, eight resections of tumor recurrence, and four conservative procedures. There was one operative death in this group. Significant morbidity was noted in the group but was clustered in a small number of patients operated on early in the series. The median follow-up in this series was 13 months (range, two to 51 months). Nineteen (65%) of the patients are surviving at a median follow-up of ten months (range, two to 51 months). The median survival (following resection) in the ten patients (35%) who died was 18 months. In 15 (52%) of the patients, a complete resection was performed. In this group, the survival is 80% with a median follow-up of 11 months. Seven (37%) are surviving with no evidence of disease. Palliation of symptoms occurred in 23 (79%) of the 29 patients. Radical resection of tumor recurrence in the pelvis can be performed with acceptable mortality and complication rates. This therapy should be considered for further clinical trials combining surgical and adjuvant therapy in patients with regional pelvic tumor recurrence.

(Arch Surg 1987;122:457-460)

Author Affiliations
From the Department of Surgery, Harvard Medical School, New England Deaconess Hospital, Boston.

Footnotes
Accepted for publication Dec 16, 1986.

Read before the 67th Annual Meeting of the New England Surgical Society, Dixville Notch, NH, Sept 28, 1986.

Reprint requests to Suite 3A, 110 Francis St, Boston, MA 02215 (Dr Benotti).

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