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Leonard B. Miller, MD; Glenn Steele, MD; Blake Cady, MD; Francis G. Wolfort, MD; Albert Bothe, Jr, MD

Arch Surg. 1987;122(4):461-466.

Abstract
• With increased use of primary radiation therapy for treatment of cancer and adjuvant radiation therapy after surgical removal of a bulk tumor, recurrence in these fields has posed significant new and increasingly technical and biologic problems. We report our experience with ten such cases in which difficult wounds were reconstructed immediately after major regional resections of advanced or recurrent tumors in fields of previous irradiation. All of these patients could undergo extirpation of their recurrent tumors in irradiated fields because of improved techniques in reconstructive flap surgery allowing large amounts of well-vascularized tissue to be transferred, sometimes over a significant distance. Follow-up of these patients has ranged from three to 18 months (median, nine months). Primary healing, decreased deformity, reduced morbidity, and prolonged disease-free intervals have been achieved with the combination of extirpative and reconstructive techniques.

(Arch Surg 1987;122:461-466)

Author Affiliations
From the Department of Surgery, Harvard Medical School, Boston.

Footnotes
Accepted for publication Dec 17, 1986.

Read before the 67th Annual Meeting of the New England Surgical Society, Dixville Notch, NH, Sept 28, 1986.

Reprint requests to 110 Francis St, Boston, MA 02215 (Dr Steele).

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