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Evidence of Underlying Reticuloendothelial Cell Dysfunction

Gerald Y. Minuk, MD; Lindsay E. Nicole, MD; T. Sherman, MD

Arch Surg. 1987;122(8):906-908.

Abstract
• Evidence of underlying liver disease and reticuloendothelial system dysfunction was sought in five adults with histories of idiopathic or "cryptogenic" liver abscess. Although no evidence of underlying liver disease was obtained (median follow-up, 3.4 years; range, 2.1 to 4.8 years), four of five individuals demonstrated a marked impairment in their ability to clear antibody-tagged erythrocytes from the systemic circulation. The results of this study suggest that patients who develop cryptogenic abscesses of the liver have an underlying reticuloendothelial cell defect that may predispose them to liver abscess formation.

(Arch Surg 1987;122:906-908)

Author Affiliations
From the Department of Medicine, University of Calgary, Calgary, Alberta.

Footnotes
Accepted for publication July 22, 1986.

Reprint requests to Department of Medicine, University of Calgary, 3330 Hospital Dr NW, Calgary, Alberta, Canada T2N 4N1 (Dr Minuk).

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