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Granulocyte Chemiluminescence in Patients With Postoperative Infections
Matti Salo, MD;
Juha Perttilä, MD;
Olli-Pekka Lehtonen, MD
Arch Surg. 1988;123(1):17-22.
Abstract
• In patients with postoperative infections, the oxygen-dependent microbicidal responses of separated granulocytes to a microbe isolated from each patient, a strain of Escherichia coli, and zymosan were evaluated by luminol-enhanced chemiluminescence. In patients with major postoperative infection, chemiluminescence responses to all particles were depressed, but no such changes were seen in patients with minor postoperative infection. No specific depression was seen in chemiluminescence responses to the isolated bacteria. The decreases found in chemiluminescence responses were not likely to be due to the operation, but at the time of measurement were probably due to the infection and reflect the depressed microbicidal capacity of granulocytes.
(Arch Surg 1988;123:17-22)
Author Affiliations
From the Departments of Anesthesiology (Drs Salo and Perttilä and Medical Microbiology (Dr Lehtonen), University of Turku (Finland).
Footnotes
Accepted for publication July 8, 1987.
Read in part at the Seventh European Congress of Anesthesiology, Vienna, Sept 9, 1986.
Reprint requests to Department of Anesthesiology, Turku University Central Hospital, SF-20520 Turku, Finland (Dr Salo).
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