Pseudohyperparathyroidism secondary to gigantic mammary hypertrophy
J. A. Van Heerden, H. Gharib and I. T. Jackson
Section of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN 55905.
Pseudohyperparathyroidism encompasses both ectopic hyperparathyroidism and
the more commonly encountered nonparathyroid humoral hypercalcemia of
malignancy--metastatic breast cancer being the classic example. Benign
breast disease is a rare cause of hypercalcemia. We recently managed a
patient with gigantic mammary hypertrophy that occurred during pregnancy
who concomitantly manifested marked nonparathyroid hypercalcemia. This
report strongly suggests that a casual relationship exists between benign
breast disease and hypercalcemia.
