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Jon A. Van Heerden, MB,ChB (Cape Town), FRCS(C); Hossein Gharib, MD; Ian T. Jackson, MB,ChB, FRCS

Arch Surg. 1988;123(1):80-82.

Abstract
• Pseudohyperparathyroidism encompasses both ectopic hyperparathyroidism and the more commonly encountered nonparathyroid humoral hypercalcemia of malignancy—metastatic breast cancer being the classic example. Benign breast disease is a rare cause of hypercalcemia. We recently managed a patient with gigantic mammary hypertrophy that occurred during pregnancy who concomitantly manifested marked nonparathyroid hypercalcemia. This report strongly suggests that a causal relationship exists between benign breast disease and hypercalcemia.

(Arch Surg 1988;123:80-82)

Author Affiliations
From the Section of Gastroenterologic and General Surgery (Dr Van Heerden), the Division of Endocrinology, Metabolism, and Internal Medicine (Dr Gharib), and the Section of Plastic and Reconstructive Surgery (Dr Jackson), Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Accepted for publication Jan 12, 1987.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr Van Heerden).

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