You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 123 No. 5, May 1988 TABLE OF CONTENTS
  Archives
  •  Online Features
  PAPERS READ BEFORE THE 68TH ANNUAL MEETING OF THE NEW ENGLAND SURGICAL SOCIETY, BRETTON WOODS, NH, SEPT 11 TO SEPT 13, 1987
 This Article
 •References
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Combined Kidney and Pancreas Transplantation in Diabetics

A. Benedict Cosimi, MD; Hugh Auchincloss, Jr, MD; Francis L. Delmonico, MD; Leslie Fang, MD; David M. Nathan, MD; Nina Tolkoff-Rubin, MD; Robert H. Rubin, MD; Harold C. Yang, MD; Paul S. Russell, MD

Arch Surg. 1988;123(5):621-625.


Abstract

• Kidney and pancreaticoduodenal transplantation were simultaneously performed in 12 insulin-dependent diabetic patients. These patients had advanced secondary complications, including blindness, vascular disease, and disabling neuropathy. Average posttransplant hospitalization and charges were 17.7 days and $42 780 compared with 11.2 days and $29 000 for patients who received renal allografts alone. Following transplantation, blood glucose and glycosylated hemoglobin A levels promptly returned to normal in all patients. Two patients subsequently died, one after five months of a cytomegalovirus infection and one after seven months of a ruptured bladder. After a mean of 11.6 months of follow-up, ten patients (83%) remained independent of insulin and dialysis. The success of pancreas transplantation in diabetics with advanced complications now approaches that of other organ allografts. It therefore appears reasonable to recommend transplantation for diabetics with less severe secondary complications, since these candidates are most likely to realize the potential benefits of long-term normoglycemia.

(Arch Surg 1988;123:621-625)



Author Affiliations

From the Transplantation Unit, Massachusetts General Hospital (Drs Cosimi, Auchincloss, Delmonico, Fang, Nathan, Tolkoff-Rubin, Rubin, Russell, and Yang), and the Departments of Surgery (Drs Cosimi, Auchincloss, Delmonico, Russell, and Yang) and Medicine (Drs Fang, Nathan, Tolkoff-Rubin, and Rubin), Harvard Medical School, Boston.


Footnotes

Accepted for publication Jan 27, 1988.

Read before the Annual Meeting of the New England Surgical Society, Bretton Woods, NH, Sept 11, 1987.

Reprint requests to Department of Surgery, Massachusetts General Hospital, Boston, MA 02114 (Dr Cosimi).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Isolated Pancreas Transplantation for Type 1 Diabetes: A Doctor's Dilemma
Nathan
JAMA 2003;290:2861-2863.
FULL TEXT  

Peripheral Vascular Disease After Kidney-Pancreas Transplantation in Diabetic Patients With End-stage Renal Disease
Morrissey et al.
Arch Surg 1997;132:358-362.
ABSTRACT  

Combined Kidney and Pancreas Transplantation: A 3-Year Experience
Shaffer et al.
Arch Surg 1992;127:574-578.
ABSTRACT  

Long-term Glucose Control in Patients with Pancreatic Transplants
Morel et al.
ANN INTERN MED 1991;115:694-699.
ABSTRACT  

Combined Kidney and Pancreas Transplantation: A Safe and Effective Treatment for Diabetic Nephropathy
Schulak et al.
Arch Surg 1990;125:881-885.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1988 American Medical Association. All Rights Reserved.