This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (66)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Predictors of Multicentricity and Microinvasion and Implications for Treatment

Gordon F. Schwartz, MD; Arthur S. Patchefsky, MD; Sidney D. Finklestein, MD; Sae H. Sohn, MD; Anthony Prestipino, MD; Stephen A. Feig, MD; Jodi S. Singer, MD

Arch Surg. 1989;124(1):29-32.

Abstract
• Fifty breasts with nonpalpable ductal carcinoma in situ (DCIS) were examined for the presence of microinvasion, multicentricity, and number of involved ducts to see if the biopsy specimen could have predicted the findings in the remainder of the breast. When DCIS was an incidental finding, fewer ducts were involved and no evidence of either microinvasion or multicentricity was found. Solid and cribriform DCIS were rarely multicentric or microinvasive; micropapillary DCIS was often multicentric, rarely microinvasive; comedocarcinoma was more likely to be both microinvasive and multicentric. Ductal carcinoma in situ as an incidental finding may be treated by excision alone; papillary and micropapillary DCIS are best treated by therapy aimed at the entire breast, although axillary dissection may not be required. Therapy for comedocarcinomas should include the entire breast and the axillary nodes.

(Arch Surg 1989;124:29-32)

Author Affiliations
From the Departments of Surgery (Drs Schwartz, Sohn, and Singer), Pathology (Drs Patchefsky and Prestipino), and Radiology (Dr Feig), Jefferson Medical College; and the Department of Pathology, Hahnemann University (Dr Finklestein), Philadelphia. Dr Patchefsky is now with Hahnemann University, Philadelphia.

Footnotes
Accepted for publication Sept 2, 1988.

Read in part before the Annual Meeting of the Society of Surgical Oncology, New Orleans, May 23, 1988.

Reprint requests to 1015 Chestnut St, Suite 510, Philadelphia, PA 19107 (Dr Schwartz).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Current Management of Patients with Ductal Carcinoma-in-Situ
Chabner et al.
The Oncologist 1997;2:76-82.
ABSTRACT | FULL TEXT  

Surgical Treatment of Ductal Carcinoma In Situ of the Breast: 10- to 20-Year Follow-up
Simpson et al.
Arch Surg 1992;127:468-472.
ABSTRACT  

Occult Breast Cancer Presenting With Axillary Metastases: Updated Management
Baron et al.
Arch Surg 1990;125:210-214.
ABSTRACT