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Results of a 20-Year Experience

Bruce G. Haffty, MD; Neal B. Goldberg, MD; Marie Rose, PA; Barbara Heil, PA; Diana Fischer, PhD; Malcolm Beinfield, MD; Charles McKhann, MD; Joseph B. Weissberg, MD

Arch Surg. 1989;124(11):1266-1270.

Abstract
• Conservative surgery and radiation therapy have been increasingly utilized at Yale–New Haven (Conn) Hospital since the 1960s. This analysis represents our experience from 1962 to 1982, with a total of 281 patients having a minimum assessable follow-up of five years and a median follow-up of 7.4 years. Five- and ten-year actuarial survivals were 83% and 67%, respectively. The actuarial breast recurrence-free rate was 91% at five years and 80% at ten years. Of 31 patients having recurrences in the breast alone, the actuarial five-year survival following recurrence was 48%. Twenty-eight (90%) of these 31 recurrences were salvageable with mastectomy or repeated wedge resection. Patients experiencing an early breast recurrence (less than three years) following initial treatment had a poorer prognosis than patients having recurrences later.

(Arch Surg 1989;124:1266-1270)

Author Affiliations
From the Departments of Therapeutic Radiology (Drs Haffty, Goldberg, and Weissberg), Surgery (Drs Beinfield and McKhann), and Biostatistics (Dr Fischer), Yale University School of Medicine, New Haven, Conn; and the Department of Surgery (Mss Rose and Heil and Dr Beinfield), Norwalk (Conn) Hospital.

Footnotes
Accepted for publication Sept 1, 1988.

Reprint requests to Department of Therapeutic Radiology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510 (Dr Haffty).

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