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Soft-Tissue Sarcomas of the Proximal Lower Extremity
Constantine P. Karakousis, MD, PhD;
Lawrence J. Emrich, PhD;
Deborah S. Vesper, RN
Arch Surg. 1989;124(11):1297-1300.
Abstract
• Of 54 patients with soft-tissue sarcomas of the proximal part of the lower extremity, 2 patients (4%) were treated with amputation, while 52 patients (96%) were treated with limb-preserving resection. Adjuvant postoperative irradiation was applied selectively when the minimum margin was less than 2 cm (22 patients). Technical improvements in exposure, resection of involved vessels or nerve, and preservation of function permitted a high rate of limb salvage with satisfactory function. At a median follow-up of 30 months for those subjects still alive, the 5-year disease-free survival rate was 65%, and only 3 patients (6%) had had a local recurrence.
(Arch Surg. 1989;124:1297-1300)
Author Affiliations
From the Departments of Surgical Oncology (Dr Karakousis and Ms Vesper) and Biomathematics (Dr Emrich), Roswell Park Memorial Institute, Buffalo, NY.
Footnotes
Accepted for publication April 17, 1989.
Reprint requests to Department of Surgical Oncology, Roswell Park Memorial Institute, 666 Elm St, Buffalo, NY 14263 (Dr Karakousis).
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