 |
|
Oxygen Delivery in Patients With Adult Respiratory Distress Syndrome Who Undergo SurgeryCorrelation With Multiple–System Organ Failure
H. Gill Cryer, MD, PhD;
J. David Richardson, MD;
Sarah Longmire-Cook, MD;
C. Matthew Brown, MD
Arch Surg. 1989;124(12):1378-1385.
Abstract
• Identification of the physiologic determinants of survival in patients with adult respiratory distress syndrome (ARDS) has been largely unsuccessful. We evaluated multiple physiologic variables over the first three reversible phases of ARDS. A stepwise multivariant linear regression analysis was used to identify correctable physiologic correlates with survival. Our goal was improved survival. We found that the oxygen delivery and alveolar-arterial oxygen gradient on the third day after the diagnosis of ARDS were the two most important correctable correlates. Both eventually effected the development of multiple–system organ failure and survival. These data provide clinical evidence that optimization of both the oxygen delivery and alveolar-arterial oxygen gradient after the onset of ARDS may allow resolution of ARDS, prevent additional organ dysfunction, and improve survival.
(Arch Surg. 1989;124:1378-1385)
Author Affiliations
From the Department of Surgery, University of Louisville (Ky) School of Medicine and the Trauma Program in Surgery, Humana Hospital University, Louisville.
Footnotes
Accepted for publication August 13, 1989.
Read before the Ninth Annual Meeting of the Surgical Infection Society, Denver, Colo, April 13, 1989.
Reprint requests to Department of Surgery, University of Louisville, 550 S Jackson St, Louisville, KY 40292 (Dr Cryer).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Prospective Trial of Supranormal Values as Goals of Resuscitation in Severe Trauma
Fleming et al.
Arch Surg 1992;127:1175-1181.
ABSTRACT
|
