 |
|
Guidelines for Practical Utilization of Intraoperative Frozen Sections
Marianne U. Prey, MD;
Thomas Vitale, MD;
Scott A. Martin, MD
Arch Surg. 1989;124(3):331-335.
Abstract
• We reviewed 4057 intraoperative frozen sections from 1980 through 1984 to assess the accuracy, strengths, and weaknesses of this technique. Breast, lymph node, and skin comprised half of the sites evaluated. Frozen-section and final diagnoses agreed in 91.5% and disagreed in 6.8% of the cases; 1.7% of the cases were deferred. False-negative frozen-section diagnoses were due to pathologist sampling or judgment errors and surgeon sampling errors. There were eight (0.15%) false-positive diagnoses, none of which altered patient treatment. We recommend that lymph nodes for lymphoproliferative disorders and breast tissue for which a malignant diagnosis will not result in an immediate mastectomy not be submitted for frozen-section diagnosis. Appropriate studies of these tissues can be carried out without an intraoperative diagnosis; such a policy will increase the cost-effectiveness of frozen sections without compromising patient care.
(Arch Surg 1989;124:331-335)
Author Affiliations
From the Departments of Pathology, St Louis University (Dr Prey) and St John's Mercy Medical Center (Drs Prey and Martin), St Louis; and the Department of Surgery, Holmes Regional Medical Center, Melbourne, Fla (Dr Vitale). Dr Prey is now with SmithKlein Bio-Science Laboratories, St Louis.
Footnotes
Accepted for publication Dec 18, 1987.
Reprints not available.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Accuracy of frozen section in the diagnosis of liver mass lesions
Rakha et al.
J. Clin. Pathol. 2006;59:352-354.
ABSTRACT
| FULL TEXT
Evaluation of the Performance and Clinical Impact of a Rapid Intraoperative Parathyroid Hormone Assay in Conjunction with Preoperative Imaging and Concise Parathyroidectomy
Johnson et al.
Clin. Chem. 2001;47:919-925.
ABSTRACT
| FULL TEXT
|
