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Miin-Fu Chen, MD; Tsann-Long Hwang, MD; Long-Bin Benjamin Jeng, MD; Yi-Yin Jan, MD; Chia-Siu Wang, MD; Fong-Fu Chou, MD

Arch Surg. 1989;124(9):1025-1028.

Abstract
• During the 11-year period from 1977 through 1987, hepatic resections were carried out in 120 patients with hepatocellular carcinoma (HCC). Twenty-five had HCCs smaller than 5 cm in diameter. There were 97 male and 23 female patients, with an average age of 51.5 years. Among them, 45.8% had liver cirrhosis and 80.8% were positive for hepatitis B surface antigen. Fourteen with ruptured HCCs underwent hepatic resection to control the intra-abdominal hemorrhage. Operative mortality within one month after surgery was 4.1%. The postoperative course was complicated by pleural effusion in 5.8%, subphrenic abscess in 2.5%, postoperative bleeding in 1.6%, hepatic failure in 1.6%, and bile leakage in 0.8% of the patients. The overall five-year survival rate in this series was 25.9%, while survival for the last five years was better (42.3% vs 11.9% for patients treated between 1977 and 1982). The cumulative survival rate had no relation to tumor rupture or liver cirrhosis. The group of patients with smaller tumors (diameter, < 5 cm) or without vascular invasion by tumor had better survival.

(Arch Surg 1989;124:1025-1028)

Author Affiliations
From the Department of Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.

Footnotes
Accepted for publication Oct 17, 1988.

Reprint requests to Department of Surgery, Chang Gung Memorial Hospital, 199 Tung-Hwa North Rd, Taipei, Taiwan, Republic of China (Dr Chen).

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