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Mark P. Sawicki, MD; Thomas J. Howard, MD; Marci Dalton; Bruce E. Stabile, MD; Edward Passaro, Jr, MD

Arch Surg. 1990;125(12):1584-1587.

Abstract
• Our experience with 47 sporadic gastrinomas suggests that no less than 85% of these tumors are located to the right of the superior mesenteric artery. This finding is unexpected because approximately 75% of insulinomas and glucagonomas are located to the left of the superior mesenteric artery. All of our extrapancreatic gastrinomas have been located to the right. These observations prompted us to determine if other extrapancreatic gastrinomas were also predominantly located to the right side. We searched the world's literature and found 10 cases of ovarian gastrinomas and one case of a renal gastrinoma. Nine of these remote extrapancreatic gastrinomas were located on the right side. This distribution of remote extrapancreatic gastrinomas is similar to our experience with peripancreatic gastrinomas. This unexpected right-sided preponderance of both remote and peripancreatic gastrinomas suggests a common origin for both.

(Arch Surg. 1990;125:1584-1587)

Author Affiliations
From the Department of Surgery, UCLA School of Medicine, and the Surgical Services of the West Los Angeles (Calif) Veterans Affairs (VA) Medical Center (Drs Sawicki, Howard, and Passaro, and Ms Dalton) and the San Diego (Calif) VA Medical Center (Dr Stabile).

Footnotes
Accepted for publication September 20, 1990.

Read before the 14th Annual Surgical Symposium of the Association of Veterans Affairs Surgeons, Charleston, SC, May 8, 1990. Reprints not avail able.

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