 |
 |

Occult Breast Cancer Presenting With Axillary MetastasesUpdated Management
Paul L. Baron, MD;
Michael P. Moore, MD;
David W. Kinne, MD;
Frank C. Candela, MD;
Michael P. Osborne, MD, MS;
Jeanne A. Petrek, MD
Arch Surg. 1990;125(2):210-214.
Abstract
 |  |
An isolated axillary lymph node metastasis in a woman without an obvious clinical primary site most frequently originates from the breast. Mastectomy has been the historical treatment of choice. A retrospective study of 35 patients was undertaken to evaluate the roles of modern mammography, breast preservation, and adjuvant systemic therapy in the management of these patients. Twenty-eight patients underwent a mastectomy, while 7 were managed by a combination of limited resection and/or axillary dissection and radiation therapy. Twenty-two (67%) of the 33 breast specimens contained carcinoma. Comparison of the pathologic results with the preoperative mammograms showed a specificity of 73%, while the sensitivity was only 29%. Actuarial 5-year survival after mastectomy or breast preservation was similar (77% and 65%, respectively). Patients with more than one positive lymph node benefited from adjuvant therapy. Mammography does not locate the majority of occult stage II breast cancers, and both breast preservation and adjuvant therapy may have roles in the management of these patients.
(Arch Surg. 1990;125:210-215)
Author Affiliations
From the Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.
Footnotes
Accepted for publication November 1, 1989.
Read before the annual meeting of the Society of Surgical Oncology, San Francisco, Calif, May 22, 1989.
Reprint requests to Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021 (Dr Kinne).
CiteULike Connotea Del.icio.us Digg Reddit Technorati
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
 |
Utility of Breast Magnetic Resonance Imaging in Patients With Occult Primary Breast Cancer
Buchanan et al.
Ann. Surg. Oncol. 2005;12:1045-1053.
ABSTRACT
| FULL TEXT
A Phase II Study of Paclitaxel plus Cisplatin Chemotherapy in an Unfavourable Group of Patients with Cancer of Unknown Primary Site
Park et al.
Jpn J Clin Oncol 2004;34:681-685.
ABSTRACT
| FULL TEXT
Cancer of Unknown Primary: Changing Approaches. A Multidisciplinary Case Presentation from the Joan Karnell Cancer Center of Pennsylvania Hospital
Mintzer et al.
The Oncologist 2004;9:330-338.
ABSTRACT
| FULL TEXT
A phase II study of cisplatin, etoposide and gemcitabine in an unfavourable group of patients with carcinoma of unknown primary site
Balana et al.
Ann Oncol 2003;14:1425-1429.
ABSTRACT
| FULL TEXT
Feasibility of Breast Preservation in the Treatment of Occult Primary Carcinoma Presenting With Axillary Metastases
Vlastos et al.
Ann. Surg. Oncol. 2001;8:425-431.
ABSTRACT
| FULL TEXT
Occult Breast Cancer Presenting Axillary Nodal Metastasis: A Case Report
Abe et al.
Jpn J Clin Oncol 2000;30:185-187.
ABSTRACT
| FULL TEXT
MR Imaging-Guided Sonography Followed by Fine-Needle Aspiration Cytology in Occult Carcinoma of the Breast
Obdeijn et al.
Am. J. Roentgenol. 2000;174:1079-1084.
ABSTRACT
| FULL TEXT
Cases of the Day : Breast Imaging Case of the Day
Cyrlak and Carpenter
RadioGraphics 1999;19:73-79.
FULL TEXT
Breast MR Imaging in Patients with Axillary Node Metastases and Unknown Primary Malignancy
Orel et al.
Radiology 1999;212:543-549.
ABSTRACT
| FULL TEXT
Cancer of Unknown Primary Origin
Briasoulis and Pavlidis
The Oncologist 1997;2:142-152.
ABSTRACT
| FULL TEXT
|