This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Lucy Wortham James Lecture

Robert A. Weinberg, PhD

Arch Surg. 1990;125(2):257-260.

Abstract
• The past three decades have witnessed enormous progress made in our understanding of the pathogenesis of cancer. Research results of the previous decades had indicated that a variety of agents, the carcinogens, could induce cancer in experimental animals. By extension, similarly acting agents were presumed to intervene in human cancer. Beyond this, the precise nature of the pathogenetic mechanisms underlying human malignancies remained obscure. In these last decades, the origins of cancer have been uncovered: specific genes and biochemical mechanisms are now known to drive the process of neoplasia.

(Arch Surg. 1990;125:257-260)

Author Affiliations
From the Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge.

Footnotes
Accepted for publication August 28, 1989.

Read before the annual meeting of the Society of Surgical Oncology, San Francisco, Calif, May 22, 1989.

Reprint requests to the Whitehead Institute of Biomedical Research, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142 (Dr Weinberg).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?