This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Kenneth W. Sharp, MD; Charles B. Ross, MD; Vicki N. Tillman; Lester F. Williams, Jr, MD

Arch Surg. 1990;125(4):460-462.

Abstract
• To our knowledge, the relationship between gallbladder volume and cystic duct function has not been studied. We hypothesized that changes in gallbladder volume would influence cystic duct resistance. The effect of gallbladder volume changes on cystic duct resistance to both prograde (emptying) and retrograde (filling) steady-state flow was tested in 12 dogs under basal cholecystokinin-stimulated conditions utilizing a multiport catheter with a highly compliant balloon placed within the gallbladder fundus. Gallbladder volume was regulated by varying balloon volume from empty to just beyond physiologic distention. Cystic duct resistance was not affected by balloon volume under basal or stimulated conditions or by the direction of perfusate flow. This study demonstrated no relationship between gallbladder volume and cystic duct resistance and did not demonstrate a cystic duct sphincter mechanism at physiologic gallbladder volumes.

(Arch Surg. 1990;125:460-462)

Author Affiliations
From the Departments of Surgery, Nashville Veterans Administration Hospital and Vanderbilt University Medical Center, Nashville, Tenn.

Footnotes
Accepted for publication October 16, 1989.

Read before the 13th Annual Meeting of the Association of Veterans Administration Surgeons, San Antonio, Tex, May 4, 1989.

Reprint requests to Department of Surgery (112), Nashville Veterans Administration Medical Center, 1310 24th Ave S, Nashville, TN 37212 (Dr Sharp).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?